Τετάρτη, 16 Νοεμβρίου 2011

Cardiac cells 'heal heart damage'

Stem cells taken from a patient's own heart have, for the first time, been used to repair damaged heart tissue, researchers claim.
The study,published in the Lancet, was designed to test the procedure's safety, but also reported improvements in the heart's ability to pump blood.
The authors said the findings were "very encouraging"
Other experts said techniques with bone marrow stem cells were more advanced and that bigger trials were needed.
The scientists say this is the first reported case of cardiac stem cells being used as a treatment in people after earlier studies had shown benefits in animals.
Improvement
The preliminary trial was on patients with heart failure who were having heart bypass surgery. During the operation, a piece of heart tissue, from the right atrial appendage, was taken.
While the patient was being sewn up, researchers isolated cardiac stem cells from the sample and cultured them until they had about two million stem cells for each patient. The cells were injected about 100 days later.
Doctors measured how efficiently the heart was pumping using the left ventricle ejection fraction - what percentage of blood was leaving one of the heart's main chamber with every beat........
......The heart is not the only source of potentially useful stem cells. Trials have already taken place using stems cells from bone marrow.
Prof Anthony Mathur, from Barts and the London School of Medicine and Dentistry, and Prof John Martin, from University College London, are already conducting large randomised clinical trials.
They are investigating the effect of giving patients stem cells from their own bone marrow, in NHS hospitals, within six hours of a heart attack......

Source: BBC Health News

1 σχόλια:

Iro Koliakou είπε...

Worldwide a lot of studies focus on the use of stem cells for the regeneration of the heart. In Greece a clinical study, that took place in AXEPA Hospital Thessaloniki, shows promising results of the use of bone marrow stem cells in patients with heart failure. http://www.translational-medicine.com/content/9/1/12
Apart from bone marrow stem cells, umbilical cord stem cells and progenitor cells derived from peripheral blood are considered as possible cells sources for heart regeneration.

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